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Oct 3, 2023

What does the body of evidence say on age-related macular degeneration (AMD) and how to treat the #1 cause of blindness in North America? Plus: which vaccines are available this fall to prevent respiratory tract infections, and a look at whether blue-light-blocking glasses will make a difference in your life!

Block 1:

(2:15) AMD: how common it is, what happens in the eye, risk factors

Block 2:

(9:20) AMD: dry AMD versus wet AMD, how to diagnose it, how to prevent it, AREDS supplements, VEGF inhibitors, lasers, rehabilitation

Block 3:

(25:54) Fall vaccines: COVID, influenza, and RSV

Block 4:

(40:19) Blue-blocking glasses


* Theme music: “Fall of the Ocean Queen“ by Joseph Hackl

* Assistant researchers: Aigul Zaripova and Ali Baghirov

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1) General background on AMD: &

2) Prevalence of AMD by age:

3) Rotterdam study:

4) EYE-RISK consortium about the Mediterranean diet:

5) The Beaver Dam Eye Study on smoking and AMD:

6) A Prospective Study of Cigarette Smoking and AMD in Women:

7) AREDS study:

8) AREDS 2 study:

9) Study linking beta-carotene to cancer in smokers:

10) Omega-3s in the VITAL study:

11) Background on anti-VEGF therapies:

12) NEJM paper comparing ranibizumab to bevacizumab:

13) 10-year outcomes of anti-VEGF therapy in AMD:

14) Cochrane review of monthly versus as-needed treatment:

15) Cochrane review on complement inhibitors for AMD:

16) Pegcetacoplan for AMD:

17) Cochrane review on photodynamic therapy for AMD:

18) Stem cells for AMD: & &

19) Jonathan’s article on blue-blocking glasses:


It’s Not Twitter, But It’ll Do:

1) Jonathan’s article on current trends in pseudoscience:

2) Jonathan quoted in the New York Times about RFK Jr.:

3) Annual meeting of the Association des communicateurs scientifiques du Québec:

4) Chris’ book, on sale now:

5) Chris’ upcoming panel at Concordia University: