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May 7, 2026

Hyaluronic acid is the most versatile ingredient in the beauty industry and promises anti-aging wrinkle-free skin for everyone. Chris and Sophie dive in to find out how much of these claims are based in evidence and whether it does anything beyond moisturizing your skin.

 

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Co-host: Sophie Tseng Pellar

Editor:    Robyn Flynn

Producer: Danielle Kaprelian

 

Theme music: “Fall of the Ocean Queen“ by Joseph Hackl

Rod of Asclepius designed by Kamil J. Przybos

Chris’ book, Does Coffee Cause Cancer?: https://ecwpress.com/products/does-coffee-cause-cancer

 

Obviously, Chris is not your doctor (probably). This podcast is not medical advice for you; it is what we call information.



References:

  1. 2022 systematic review of topical hyaluronic acid https://pmc.ncbi.nlm.nih.gov/articles/PMC10078143/

  2. A 2025 systematic review and meta-analysis of injectable hyaluronic acid https://pubmed.ncbi.nlm.nih.gov/39807700/

  3. Meta-analysis of 7 randomized controlled trials of oral supplements containing hyaluronic acid https://pubmed.ncbi.nlm.nih.gov/40911749/

  4. Large systematic reviews of skin supplements https://pmc.ncbi.nlm.nih.gov/articles/PMC9201759/

  5. Single large randomized controlled trial of 129 subjects https://pmc.ncbi.nlm.nih.gov/articles/PMC10661223/